Endocrine Abstracts

A 25-year-old Asian man presented with a 6 month history of erectile dysfunction, loss of libido and reduced exercise tolerance. His past medical history included ulcerative colitis, treated with long-term prednisolone and mesalazine for 8 years. He weighed 116 kg and his BP was 144/86 mmHg. He had bilateral gynaecomastia but no galactorrhea. Testicular volumes were 8 ml bilaterally and secondary sexual characteristics were normal. He was clinically euthyroid.<p class="abs...

Insulinomas are rare neuroendocrine tumours with an estimated incidence of up to four new cases per mill./p.a. Most tumours are benign, <2 cm and arise from the islets of Langerhans.Typically patients present with Whipple’s triad: symptoms of hypoglycaemia, caused by fasting or exercise, low plasma glucose and symptoms relieved by Food. The diagnosis is confirmed by high insulin and c-peptide levels, inappropriately high for prevailing glucose.<...